1258 children (mean 6.6 [SD 4.9] years) were hospitalized with laboratory-confirmed influenza during the study period. 10.3% percent (129/1258) had neurologic complications. While most neurologic complications were seizure (n=93) and encephalopathy (n=47), 19% (25/129) of children had other neurologic complications, including meningitis/encephalitis (n=7), ataxia (n=7), cerebral edema (n=4), movement disorder (n=3), arterial ischemic stroke (n=2), motor deficit (n=1), autonomic dysfunction (n=1), Bell’s palsy (n=1), PRES (n=1), and mutism (n=1). Median time between neurologic symptom onset and influenza test was 1 day. Children with neurologic complications were similar in age (6.1 vs 6.6 years, p=0.274) and had a similar distribution of influenza strains (H1, H3, B) compared to children without. Children with pre-existing neurologic diagnoses (668/1258) had a higher incidence of neurologic complications than those without (15% vs 5%, p<0.001), as did children with PICU admission (28% vs 6%, p<0.001).