2025 Annual Meeting | SS2 - AAN Section Showcase: Antisense Oligonucleotides in Neurogenetics: A New Frontier in Therapeutic Innovation

Date Sunday 04/06/25

Time 08:00 AM - 09:00 AM PDT Add To Calendar

Location San Diego Convention Center | 24AB

Session Format This program will be presented in-person only

On Demand This program is not expected to be available in the meeting's On Demand product.

Event Type Hubs

Director(s) Deepa S. Rajan, MD, FAAN, Andrea L. Gropman, MD, FAAN, Samuel A. Frank, MD, FAAN, Adolfo Ramirez Zamora, MD, Olivia S. Kim Mcmanus, MD

Topic(s) Child Neurology and Developmental Neurology, General Neurology, Neuromuscular and Clinical Neurophysiology (EMG)

Learning Objectives Sponsored by the Neurogenetics Section. Collaborating sections include the Neuromuscular, Experimental Neurotherapeutics, and Child Neurology Sections.
This session will discuss the mechanisms of ASOs, reviewing their clinical applications and discussing the challenges and innovations. Speakers will highlight ASOs from their field and discuss the challenges with safety, efficacy and ethics of this newly emerging therapeutic modality. The session aims to inspire clinicians and broaden the scope of therapeutic possibilities for neurogenetic disorders.

CME Available 0.00 CME credit

Program Materials Program Evaluations

Event Timeline
08:00 AM - 09:00 AM PDT	Discussion	AAN Section Showcase: Antisense Oligonucleotides in Neurogenetics: A New Frontier in Therapeutic Innovation Deepa S. Rajan, MD, FAAN, Andrea L. Gropman, MD, FAAN

Faculty Disclosures
Deepa S. Rajan, MD, FAAN	Dr. Rajan has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Rajan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi. Dr. Rajan has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Medlink Neurology. The institution of Dr. Rajan has received research support from National Scleroderma Foundation. The institution of Dr. Rajan has received research support from Denali Therapeutics. The institution of Dr. Rajan has received research support from Ultragenyx . The institution of Dr. Rajan has received research support from Regenxbio. The institution of Dr. Rajan has received research support from Takeda. The institution of Dr. Rajan has received research support from Prevail Therapeutics. The institution of Dr. Rajan has received research support from Children's Neuroscience Institute. Dr. Rajan has received intellectual property interests from a discovery or technology relating to health care.
Andrea L. Gropman, MD, FAAN	Dr. Gropman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Change Health Care. Dr. Gropman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Cyprium. Dr. Gropman has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for various legal firms. The institution of Dr. Gropman has received research support from National Institutes of Health. The institution of Dr. Gropman has received research support from O'Malley Family Foundation.
Samuel A. Frank, MD, FAAN	Dr. Frank has received personal compensation in the range of $500-$4,999 for serving as a Consultant for uniQure. Dr. Frank has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Teva. Dr. Frank has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. The institution of Dr. Frank has received research support from Huntington's Disease Society of America. The institution of Dr. Frank has received research support from Roche/Genentech. The institution of Dr. Frank has received research support from CHDI Foundation. The institution of Dr. Frank has received research support from Huntington Study Group. The institution of Dr. Frank has received research support from Cerevel.
Adolfo Ramirez Zamora, MD	Dr. Ramirez Zamora has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CNS Ratings. Dr. Ramirez Zamora has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Medtronic. Dr. Ramirez Zamora has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Rho Inc. Dr. Ramirez Zamora has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Signant Health. Dr. Ramirez Zamora has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cerevel therapeutics. Dr. Ramirez Zamora has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for NIH. The institution of Dr. Ramirez Zamora has received research support from Parkinsons Foundation.
Olivia S. Kim Mcmanus, MD	Dr. Kim Mcmanus has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biomarin. Dr. Kim Mcmanus has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biomarin. Dr. Kim Mcmanus has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Praxis Precision Medicines. Dr. Kim Mcmanus has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Stoke Therapeutics. Dr. Kim Mcmanus has received research support from California Institute for Regenerative Medicine.

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